Ribosomal DNA (rDNA); an approximately 1-2 Mb region on the right arm of chr. XII consisting of 100-200 tandem copies of a 9.1 kb repeat which contains the genes for 5S, 5.8S, 25S and 18S rRNAs (represented by the RDN37, RDN25, RDN18, RDN58, and RDN5 loci); a specific histone modification (H3K56ac) regulates RNA polymerase I transcription of the ribosomal DNA
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Functional Networks
Functional Networks display how gene products work together in biological systems. The Shared Annotations
network shows genes with similar GO annotations, suggesting functional relationships. GO-CAMs (Gene
Ontology Causal Activity Models) are manually curated pathway models that illustrate how molecular
activities of multiple gene products connect through causal relationships to carry out biological
processes. GO-CAMs integrate Molecular Function, Biological Process, and Cellular Component information
into unified pathway representations based on published experimental evidence. Click "View GO-CAM at Gene
Ontology" to explore the interactive model at AmiGO.
Click on a gene or Biological Process GO term name to go to its specific page within SGD; drag any of the gene or GO
term name objects around within the visualization for easier viewing; click “Reset” to automatically redraw the
diagram; filter the genes that share GO Biological Process terms with the given gene by the number of terms they
share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.
A summary of the locus, written by SGD Biocurators following a thorough review of the literature. Links
to gene names and curated GO terms are included within the Summary Paragraphs.
All manually curated literature for the specified gene, shown as a count of references by year of
publication followed by the most recent papers. Click "Literature Details" or "See all"
to view all literature information for this locus, organized into topics according to their
relevance to the gene (Primary Literature, Additional Literature, or Review).