Mating-type cassette - right; unexpressed complete copy of the mating-type genes, silenced by the Sir2 histone deacetylase and its associated SIR1, SIR3 and SIR4 proteins; mating-type switching involves replacement of the Ya or Yalpha sequences present at the MAT locus with either the a or alpha genes located at one of the HM loci in a process stimulated by the HO endonuclease; sequence replacement occurs by gene conversion, leaving the donor unaltered
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The S. cerevisiae Reference Genome sequence is derived from laboratory strain
S288C. Download DNA or protein sequence, view genomic context and
coordinates. Click "Sequence Details" to view all sequence information for this locus, including that
for other strains.
Functional Networks
Functional Networks display how gene products work together in biological systems. The Shared Annotations
network shows genes with similar GO annotations, suggesting functional relationships. GO-CAMs (Gene
Ontology Causal Activity Models) are manually curated pathway models that illustrate how molecular
activities of multiple gene products connect through causal relationships to carry out biological
processes. GO-CAMs integrate Molecular Function, Biological Process, and Cellular Component information
into unified pathway representations based on published experimental evidence. Click "View GO-CAM at Gene
Ontology" to explore the interactive model at AmiGO.
Click on a gene or Biological Process GO term name to go to its specific page within SGD; drag any of the gene or GO
term name objects around within the visualization for easier viewing; click “Reset” to automatically redraw the
diagram; filter the genes that share GO Biological Process terms with the given gene by the number of terms they
share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.
A summary of the locus, written by SGD Biocurators following a thorough review of the literature. Links
to gene names and curated GO terms are included within the Summary Paragraphs.
All manually curated literature for the specified gene, shown as a count of references by year of
publication followed by the most recent papers. Click "Literature Details" or "See all"
to view all literature information for this locus, organized into topics according to their
relevance to the gene (Primary Literature, Additional Literature, or Review).