ATG12-ATG5 complex

Primary Literature

Kim JH, et al. (2015) Insights into autophagosome maturation revealed by the structures of ATG5 with its interacting partners. Autophagy 11(1):75-87 PMID: 25484072
Mizushima N (2010) The role of the Atg1/ULK1 complex in autophagy regulation. Curr Opin Cell Biol 22(2):132-9 PMID: 20056399
Hanada T, et al. (2007) The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy. J Biol Chem 282(52):37298-302 PMID: 17986448
Thompson AR, et al. (2005) Autophagic nutrient recycling in Arabidopsis directed by the ATG8 and ATG12 conjugation pathways. Plant Physiol 138(4):2097-110 PMID: 16040659
Kuma A, et al. (2002) Formation of the approximately 350-kDa Apg12-Apg5.Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast. J Biol Chem 277(21):18619-25 PMID: 11897782

Reviews

Maruyama T and Noda NN (2025) Structural Insights into Autophagy in the AlphaFold Era. J Mol Biol 437(18):169235 PMID: 40441412

Metur SP and Klionsky DJ (2024) Nutrient-dependent signaling pathways that control autophagy in yeast. FEBS Lett 598(1):32-47 PMID: 37758520

Marquardt L and Thumm M (2023) Autophagic and non-autophagic functions of the Saccharomyces cerevisiae PROPPINs Atg18, Atg21 and Hsv2. Biol Chem 404(8-9):813-819 PMID: 37139661

Leary KA and Ragusa MJ (2022) Characterization of Protein-Membrane Interactions in Yeast Autophagy. Cells 11(12) PMID: 35741004

Zhang H (2022) The Genetics of Autophagy in Multicellular Organisms. Annu Rev Genet 56:17-39 PMID: 35679620

Kirkin V and Rogov VV (2019) A Diversity of Selective Autophagy Receptors Determines the Specificity of the Autophagy Pathway. Mol Cell 76(2):268-285 PMID: 31585693

Reggiori F and Ungermann C (2017) Autophagosome Maturation and Fusion. J Mol Biol 429(4):486-496 PMID: 28077293

Rubinsztein DC and Frake RA (2016) Yoshinori Ohsumi's Nobel Prize for mechanisms of autophagy: from basic yeast biology to therapeutic potential. J R Coll Physicians Edinb 46(4):228-233 PMID: 28504774

ATG12-ATG5 complex Literature TEXT HERE

Primary Literature TEXT HERE

Reviews

ATG12-ATG5 complex Literature

Primary Literature