Additional Literature
Papers that show experimental evidence for the pathway, but for which the
pathway is not the paper’s principal focus.
11
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Kandasamy P, et al. (2004)
Regulation of unsaturated fatty acid biosynthesis in Saccharomyces: the endoplasmic reticulum membrane protein, Mga2p, a transcription activator of the OLE1 gene, regulates the stability of the OLE1 mRNA through exosome-mediated mechanisms. J Biol Chem 279(35):36586-92
PMID: 15220333
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Nakagawa Y, et al. (2002)
Mga2p is a putative sensor for low temperature and oxygen to induce OLE1 transcription in Saccharomyces cerevisiae. Biochem Biophys Res Commun 291(3):707-13
PMID: 11855848
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Chellappa R, et al. (2001)
The membrane proteins, Spt23p and Mga2p, play distinct roles in the activation of Saccharomyces cerevisiae OLE1 gene expression. Fatty acid-mediated regulation of Mga2p activity is independent of its proteolytic processing into a soluble transcription activator. J Biol Chem 276(47):43548-56
PMID: 11557770
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Hoppe T, et al. (2000)
Activation of a membrane-bound transcription factor by regulated ubiquitin/proteasome-dependent processing. Cell 102(5):577-86
PMID: 11007476
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Kwast KE, et al. (1999)
Oxygen sensing in yeast: evidence for the involvement of the respiratory chain in regulating the transcription of a subset of hypoxic genes. Proc Natl Acad Sci U S A 96(10):5446-51
PMID: 10318903
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Zhang S, et al. (1999)
MGA2 or SPT23 is required for transcription of the delta9 fatty acid desaturase gene, OLE1, and nuclear membrane integrity in Saccharomyces cerevisiae. Genetics 151(2):473-83
PMID: 9927444
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Gonzalez CI and Martin CE (1996)
Fatty acid-responsive control of mRNA stability. Unsaturated fatty acid-induced degradation of the Saccharomyces OLE1 transcript. J Biol Chem 271(42):25801-9
PMID: 8824209
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Mitchell AG and Martin CE (1995)
A novel cytochrome b5-like domain is linked to the carboxyl terminus of the Saccharomyces cerevisiae delta-9 fatty acid desaturase. J Biol Chem 270(50):29766-72
PMID: 8530368
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McDonough VM, et al. (1992)
Specificity of unsaturated fatty acid-regulated expression of the Saccharomyces cerevisiae OLE1 gene. J Biol Chem 267(9):5931-6
PMID: 1556107
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Stukey JE, et al. (1990)
The OLE1 gene of Saccharomyces cerevisiae encodes the delta 9 fatty acid desaturase and can be functionally replaced by the rat stearoyl-CoA desaturase gene. J Biol Chem 265(33):20144-9
PMID: 1978720
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Bossie MA and Martin CE (1989)
Nutritional regulation of yeast delta-9 fatty acid desaturase activity. J Bacteriol 171(12):6409-13
PMID: 2687232
Reviews 2
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Martin CE, et al. (2007)
Regulation of long chain unsaturated fatty acid synthesis in yeast. Biochim Biophys Acta 1771(3):271-85
PMID: 16920014
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Aguilar PS and de Mendoza D (2006)
Control of fatty acid desaturation: a mechanism conserved from bacteria to humans. Mol Microbiol 62(6):1507-14
PMID: 17087771