FIG2 / YCR089W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

Non-essential gene in reference strain S288C; null mutant causes chromosome instability and defective mating with abnormal cell fusion, mating projection morphology, and nuclear fusion; exhibits cell wall stress with increased Slt2p phosphorylation and abnormal spindle organization that is partially suppressed by osmotic support; shows context-dependent mating efficiency defects and decreased viability during mating; decreased resistance to multiple compounds and decreased competitive fitness in minimal medium; overexpression promotes filamentous growth and adhesion in Sigma1278b; the null mutant of paralog AGA1 is viable; the fig2 aga1 double mutant is viable but sterile; the fig2 aga1 aga2 triple mutant and the fig2 aga1 sag1 triple mutant are also viable but sterile

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources